Articoli Scientifici di Oftalmologia
Argomento : 2
Corneal Epithelium Thickness Profile in 614 Normal Chinese Children Aged 7–15
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The purpose of the study is to describe the values and distribution of corneal epithelium thickness
(CET) in normal Chinese school-aged children, and to explore associated factors with CET. CET maps
were measured by Fourier-domain optical coherence tomography (FD-OCT) in normal Chinese children
aged 7 to 15 years old from two randomly selected schools in Shanghai, China.
Children with normal
intraocular pressure were further examined for cycloplegic autorefraction, corneal curvature radius
(CCR) and axial length. Central (2-mm diameter area), para-central (2- to 5-mm diameter area), and
peripheral (5- to 6-mm diameter area) CET in the superior, superotemporal, temporal, inferotemporal,
inferior, inferonasal, nasal, superonasal cornea; minimum, maximum, range, and standard deviation
of CET within the 5-mm diameter area were recorded.
The CET was thinner in the superior than in the
inferior and was thinner in the temporal than in the nasal. The maximum CET was located in the inferior
zone, and the minimum CET was in the superior zone. A thicker central CET was associated with male
gender (p=0.009) and older age (p=0.037) but not with CCR (p=0.061), axial length (p=0.253), or
refraction (p=0.351) in the multiple regression analyses. CCR, age, and gender were correlated with
para-central and peripheral CET
